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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 12' and Ligand = 'BDBM342101'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 12


(Homo sapiens (Human))		BDBM342101
PNG
(3-((4-((4-(3-(3-(tert-Butyl)-1-methyl-1H-pyrazol-5...)
Show SMILES Cn1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3cc(cc(c3)C(=O)NCCN3CCOCC3)C#C)n2)c2ccccc12)C(C)(C)C
Show InChI InChI=1S/C38H41N9O4/c1-6-25-21-26(35(48)39-15-16-47-17-19-50-20-18-47)23-27(22-25)41-36-40-14-13-34(44-36)51-31-12-11-30(28-9-7-8-10-29(28)31)42-37(49)43-33-24-32(38(2,3)4)45-46(33)5/h1,7-14,21-24H,15-20H2,2-5H3,(H,39,48)(H,40,41,44)(H2,42,43,49)
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MMDB

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US Patent
n/an/a 5n/an/an/an/an/an/a



TOPIVERT PHARMA LIMITED; RESPIVERT LIMITED

US Patent


Assay Description
p38 MAPKγ: The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashio...

US Patent US9771353 (2017)


BindingDB Entry DOI: 10.7270/Q2HQ4219
More data for this
Ligand-Target Pair