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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 12' and Ligand = 'BDBM342108'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 12


(Homo sapiens (Human))		BDBM342108
PNG
(3-((4-((4-(3-(3-(tert-Butyl)-1-ethyl-1H-pyrazol-5-...)
Show SMILES CCn1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3cc(cc(c3)C(=O)NCCOCCOCCOC)C#C)n2)c2ccccc12)C(C)(C)C
Show InChI InChI=1S/C40H46N8O6/c1-7-27-23-28(37(49)41-17-18-52-21-22-53-20-19-51-6)25-29(24-27)43-38-42-16-15-36(46-38)54-33-14-13-32(30-11-9-10-12-31(30)33)44-39(50)45-35-26-34(40(3,4)5)47-48(35)8-2/h1,9-16,23-26H,8,17-22H2,2-6H3,(H,41,49)(H,42,43,46)(H2,44,45,50)
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US Patent
n/an/a 20n/an/an/an/an/an/a



TOPIVERT PHARMA LIMITED; RESPIVERT LIMITED

US Patent


Assay Description
p38 MAPKγ: The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashio...

US Patent US9771353 (2017)


BindingDB Entry DOI: 10.7270/Q2HQ4219
More data for this
Ligand-Target Pair