Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 12' and Ligand = 'BDBM342110'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 12 (Homo sapiens (Human))	BDBM342110 (3-Ethynyl-5-((4-((4-(3-(3-isopropyl-1-methyl-1H-py...) Show SMILES CC(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4cc(cc(c4)C(=O)NCCN4CCOCC4)C#C)n3)c3ccccc23)n(C)n1 Show InChI InChI=1S/C37H39N9O4/c1-5-25-20-26(35(47)38-14-15-46-16-18-49-19-17-46)22-27(21-25)40-36-39-13-12-34(43-36)50-32-11-10-30(28-8-6-7-9-29(28)32)41-37(48)42-33-23-31(24(2)3)44-45(33)4/h1,6-13,20-24H,14-19H2,2-4H3,(H,38,47)(H,39,40,43)(H2,41,42,48)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TOPIVERT PHARMA LIMITED; RESPIVERT LIMITED US Patent					Assay Description p38 MAPKγ: The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashio...				US Patent US9771353 (2017) BindingDB Entry DOI: 10.7270/Q2HQ4219
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