Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM16401'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM16401 (5-[3-(1-methylcyclopropyl)-[1,2,4]triazolo[3,4-a]p...) Show SMILES CC1(CC1)c1nnc2ccc(cn12)-c1ocnc1-c1cc(F)c(F)cc1F Show InChI InChI=1S/C19H13F3N4O/c1-19(4-5-19)18-25-24-15-3-2-10(8-26(15)18)17-16(23-9-27-17)11-6-13(21)14(22)7-12(11)20/h2-3,6-9H,4-5H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...				Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ
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