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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM205294'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM205294
PNG
(US9249125, 47)
Show SMILES COc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4[nH]nc(C(=O)N(C)C)c4c3)n2)c2ccccc12)C(C)(C)C
Show InChI InChI=1S/C39H38N10O4/c1-39(2,3)32-22-33(49(47-32)24-12-14-25(52-6)15-13-24)43-38(51)42-29-17-18-31(27-10-8-7-9-26(27)29)53-34-19-20-40-37(44-34)41-23-11-16-30-28(21-23)35(46-45-30)36(50)48(4)5/h7-22H,1-6H3,(H,45,46)(H,40,41,44)(H2,42,43,51)
PDB
MMDB

NCI pathway
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KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/a 32n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the l...


US Patent US9249125 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72QG
More data for this
Ligand-Target Pair