Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM205303'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM205303 (US9249125, 56) Show SMILES Cc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4cccc(OCCN5CCOCC5)c4)C(C)(C)C)c4ccccc34)n2)cc2cn[nH]c12 Show InChI InChI=1S/C42H44N10O4/c1-27-22-29(23-28-26-44-49-39(27)28)45-40-43-15-14-38(48-40)56-35-13-12-34(32-10-5-6-11-33(32)35)46-41(53)47-37-25-36(42(2,3)4)50-52(37)30-8-7-9-31(24-30)55-21-18-51-16-19-54-20-17-51/h5-15,22-26H,16-21H2,1-4H3,(H,44,49)(H,43,45,48)(H2,46,47,53)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the l...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
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