Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM205308'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM205308 (US9249125, 61) Show SMILES CC(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5CC(=O)Nc5c4)n3)c3ccccc23)n(n1)-c1ccc(OCCN2CCOCC2)cc1 Show InChI InChI=1S/C41H41N9O5/c1-26(2)34-25-37(50(48-34)29-9-11-30(12-10-29)54-22-19-49-17-20-53-21-18-49)46-41(52)45-33-13-14-36(32-6-4-3-5-31(32)33)55-39-15-16-42-40(47-39)43-28-8-7-27-23-38(51)44-35(27)24-28/h3-16,24-26H,17-23H2,1-2H3,(H,44,51)(H,42,43,47)(H2,45,46,52)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the l...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
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