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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM247091'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM247091
PNG
(N-(2-(dimethylamino)ethyl)-4-((4-((4-(3-(3-isoprop...)
Show SMILES COc1cc(ccc1Nc1nccc(Oc2ccc(NC(=O)Nc3cc(nn3-c3ccc(C)cc3)C(C)C)c3ccccc23)n1)C(=O)NCCN(C)C
Show InChI InChI=1S/C40H43N9O4/c1-25(2)33-24-36(49(47-33)28-14-11-26(3)12-15-28)45-40(51)44-31-17-18-34(30-10-8-7-9-29(30)31)53-37-19-20-42-39(46-37)43-32-16-13-27(23-35(32)52-6)38(50)41-21-22-48(4)5/h7-20,23-25H,21-22H2,1-6H3,(H,41,50)(H,42,43,46)(H2,44,45,51)
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US Patent
n/an/a<1n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...

US Patent US9701670 (2017)


BindingDB Entry DOI: 10.7270/Q2JM2CP2
More data for this
Ligand-Target Pair