BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM247100'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM247100
PNG
(3-((4-((4-(3-(3-isopropyl-1-(p-tolyl)-1H-pyrazol-5...)
Show SMILES CC(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4cc(C)cc(c4)C(=O)NCCN4CCOCC4)n3)c3ccccc23)n(n1)-c1ccc(C)cc1
Show InChI InChI=1S/C42H45N9O4/c1-27(2)36-26-38(51(49-36)32-11-9-28(3)10-12-32)47-42(53)46-35-13-14-37(34-8-6-5-7-33(34)35)55-39-15-16-44-41(48-39)45-31-24-29(4)23-30(25-31)40(52)43-17-18-50-19-21-54-22-20-50/h5-16,23-27H,17-22H2,1-4H3,(H,43,52)(H,44,45,48)(H2,46,47,53)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<1n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...

US Patent US9701670 (2017)


BindingDB Entry DOI: 10.7270/Q2JM2CP2
More data for this
Ligand-Target Pair