Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM25987'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM25987 (N-[(4-methanesulfonamidophenyl)methyl]-4-[2-methyl...) Show SMILES Cc1nnc(o1)-c1ccc(C)c(c1)-c1ccc(cc1)C(=O)NCc1ccc(NS(C)(=O)=O)cc1 Show InChI InChI=1S/C25H24N4O4S/c1-16-4-7-21(25-28-27-17(2)33-25)14-23(16)19-8-10-20(11-9-19)24(30)26-15-18-5-12-22(13-6-18)29-34(3,31)32/h4-14,29H,15H2,1-3H3,(H,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	40	-41.8	280	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description Fluorescence polarization assays used GST-tagged enzyme and an ATP-competitive Rhodamine-green labelled fluoroligand. These components were dissolved...				Bioorg Med Chem Lett 18: 324-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.043 BindingDB Entry DOI: 10.7270/Q2FX77RC
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