Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM25991'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM25991 (N-[(4-chlorophenyl)methyl]-4-[2-methyl-5-(5-methyl...) Show SMILES Cc1nnc(o1)-c1ccc(C)c(c1)-c1ccc(cc1)C(=O)NCc1ccc(Cl)cc1 Show InChI InChI=1S/C24H20ClN3O2/c1-15-3-6-20(24-28-27-16(2)30-24)13-22(15)18-7-9-19(10-8-18)23(29)26-14-17-4-11-21(25)12-5-17/h3-13H,14H2,1-2H3,(H,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	100	-39.6	600	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description Fluorescence polarization assays used GST-tagged enzyme and an ATP-competitive Rhodamine-green labelled fluoroligand. These components were dissolved...				Bioorg Med Chem Lett 18: 324-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.043 BindingDB Entry DOI: 10.7270/Q2FX77RC
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