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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50156737'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50156737
PNG
((S)-N-isopropyl-4-methyl-3-(4-(methyl(neopentyl)-a...)
Show SMILES CC(C)NC(=O)c1ccc(C)c(Nc2nc(N[C@H]3CCNC3)nc(n2)N(C)CC(C)(C)C)c1 |r|
Show InChI InChI=1S/C24H38N8O/c1-15(2)26-20(33)17-9-8-16(3)19(12-17)28-22-29-21(27-18-10-11-25-13-18)30-23(31-22)32(7)14-24(4,5)6/h8-9,12,15,18,25H,10-11,13-14H2,1-7H3,(H,26,33)(H2,27,28,29,30,31)/t18-/m0/s1
PDB
MMDB

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PC cid
PC sid
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Patents

Article
PubMed
n/an/a 51n/an/an/an/an/an/a



Bristol-Myers Squibb

Curated by ChEMBL


Assay Description
Inhibition of human p38-alpha expressed in Escherichia coli


J Med Chem 47: 6283-91 (2004)


Article DOI: 10.1021/jm049521d
BindingDB Entry DOI: 10.7270/Q2WS8SR1
More data for this
Ligand-Target Pair