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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50262975'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50262975
PNG
(4'-Hydrazinocarbonyl-6-methyl-biphenyl-3-carboxyli...)
Show SMILES Cc1ccc(cc1-c1ccc(cc1)C(=O)NN)C(=O)NC1CC1
Show InChI InChI=1S/C18H19N3O2/c1-11-2-3-14(17(22)20-15-8-9-15)10-16(11)12-4-6-13(7-5-12)18(23)21-19/h2-7,10,15H,8-9,19H2,1H3,(H,20,22)(H,21,23)
PDB
MMDB

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Article
PubMed
97n/an/an/an/an/an/an/an/a



GlaxoSmithKline R&D

Curated by ChEMBL


Assay Description
Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...


Bioorg Med Chem Lett 18: 4428-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.048
BindingDB Entry DOI: 10.7270/Q2CR5T5P
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50262975
PNG
(4'-Hydrazinocarbonyl-6-methyl-biphenyl-3-carboxyli...)
Show SMILES Cc1ccc(cc1-c1ccc(cc1)C(=O)NN)C(=O)NC1CC1
Show InChI InChI=1S/C18H19N3O2/c1-11-2-3-14(17(22)20-15-8-9-15)10-16(11)12-4-6-13(7-5-12)18(23)21-19/h2-7,10,15H,8-9,19H2,1H3,(H,20,22)(H,21,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 610n/an/an/an/an/an/a



GlaxoSmithKline R&D

Curated by ChEMBL


Assay Description
Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...


Bioorg Med Chem Lett 18: 4428-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.048
BindingDB Entry DOI: 10.7270/Q2CR5T5P
More data for this
Ligand-Target Pair