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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50308760'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50308760
PNG
(5-(3-Fluoro-4-methylphenyl)-N-(4-methyl-3-(3-methy...)
Show SMILES Cc1ccc(cc1F)-c1nc([nH]c1C(=O)Nc1ccc(C)c(Nc2ccc3ncn(C)c(=O)c3c2)c1)C(F)(F)F
Show InChI InChI=1S/C28H22F4N6O2/c1-14-4-6-16(10-20(14)29)23-24(37-27(36-23)28(30,31)32)25(39)35-18-7-5-15(2)22(12-18)34-17-8-9-21-19(11-17)26(40)38(3)13-33-21/h4-13,34H,1-3H3,(H,35,39)(H,36,37)
PDB
MMDB

NCI pathway
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KEGG

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DrugBank
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 100n/an/an/an/an/an/a



The University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assay


Bioorg Med Chem 18: 292-304 (2010)


Article DOI: 10.1016/j.bmc.2009.10.055
BindingDB Entry DOI: 10.7270/Q2SQ90H4
More data for this
Ligand-Target Pair