Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50314791'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50314791 (3-(1-(2,6-difluorophenyl)-7-methyl-6-oxo-6,7-dihyd...) Show SMILES Cc1ccc(cc1-c1cc2cnn(-c3c(F)cccc3F)c2n(C)c1=O)C(O)=O |(-.23,-4.58,;-1.57,-3.81,;-2.9,-4.59,;-4.23,-3.82,;-4.24,-2.28,;-2.91,-1.51,;-1.57,-2.27,;-.24,-1.5,;1.1,-2.27,;2.43,-1.49,;3.89,-1.96,;4.8,-.71,;3.86,.54,;4.63,1.88,;6.12,1.96,;6.9,.61,;6.88,3.3,;6.04,4.59,;4.5,4.58,;3.84,3.23,;2.26,3.4,;2.42,.05,;1.09,.81,;1.08,2.35,;-.24,.04,;-1.58,.81,;-5.57,-1.52,;-5.58,.02,;-6.9,-2.29,)| Show InChI InChI=1S/C21H15F2N3O3/c1-11-6-7-12(21(28)29)8-14(11)15-9-13-10-24-26(19(13)25(2)20(15)27)18-16(22)4-3-5-17(18)23/h3-10H,1-2H3,(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	458	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha-mediated AFT2 phosphorylation after 1 hr by HTRF assay				J Med Chem 53: 2973-85 (2010) Article DOI: 10.1021/jm100095x BindingDB Entry DOI: 10.7270/Q2FX79MD
					More data for this Ligand-Target Pair