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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50323418'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50323418
PNG
(CHEMBL1209276 | N-(2-(3-(3-tert-butyl-5-(3-phenylu...)
Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccccc2)n(n1)-c1cccc(CNC(=O)CNC(=O)c2cccnc2)c1
Show InChI InChI=1S/C29H31N7O3/c1-29(2,3)24-16-25(34-28(39)33-22-11-5-4-6-12-22)36(35-24)23-13-7-9-20(15-23)17-31-26(37)19-32-27(38)21-10-8-14-30-18-21/h4-16,18H,17,19H2,1-3H3,(H,31,37)(H,32,38)(H2,33,34,39)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 51n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of unactive p38alpha


Bioorg Med Chem Lett 20: 4885-91 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.073
BindingDB Entry DOI: 10.7270/Q2Z31ZT2
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50323418
PNG
(CHEMBL1209276 | N-(2-(3-(3-tert-butyl-5-(3-phenylu...)
Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccccc2)n(n1)-c1cccc(CNC(=O)CNC(=O)c2cccnc2)c1
Show InChI InChI=1S/C29H31N7O3/c1-29(2,3)24-16-25(34-28(39)33-22-11-5-4-6-12-22)36(35-24)23-13-7-9-20(15-23)17-31-26(37)19-32-27(38)21-10-8-14-30-18-21/h4-16,18H,17,19H2,1-3H3,(H,31,37)(H,32,38)(H2,33,34,39)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 205n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of active p38alpha


Bioorg Med Chem Lett 20: 4885-91 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.073
BindingDB Entry DOI: 10.7270/Q2Z31ZT2
More data for this
Ligand-Target Pair