Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50341377'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50341377 (3-(2-chlorophenyl)-7-[(trans-4-hydroxycyclohexyl)a...) Show SMILES O[C@H]1CC[C@@H](CC1)Nc1ncc2CN(C(=O)Nc2n1)c1ccccc1Cl |r,wU:1.0,wD:4.7,(-8.97,.99,;-7.64,.22,;-6.31,.99,;-4.97,.22,;-4.97,-1.32,;-6.31,-2.09,;-7.64,-1.32,;-3.64,-2.09,;-2.3,-1.32,;-2.3,.22,;-.97,.99,;.36,.22,;1.7,.99,;3.03,.22,;3.03,-1.32,;4.36,-2.09,;1.7,-2.09,;.36,-1.32,;-.97,-2.09,;4.36,.99,;4.36,2.53,;5.7,3.3,;7.03,2.53,;7.03,.99,;5.7,.22,;5.7,-1.32,)| Show InChI InChI=1S/C18H20ClN5O2/c19-14-3-1-2-4-15(14)24-10-11-9-20-17(22-16(11)23-18(24)26)21-12-5-7-13(25)8-6-12/h1-4,9,12-13,25H,5-8,10H2,(H2,20,21,22,23,26)/t12-,13-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC Curated by ChEMBL					Assay Description Inhibition of p38alpha				J Med Chem 54: 2255-65 (2011) Article DOI: 10.1021/jm101423y BindingDB Entry DOI: 10.7270/Q20P109X
					More data for this Ligand-Target Pair				3D Structure (crystal)