Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50347102'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50347102 (CHEMBL1797205) Show SMILES CN1CCN(CC1)c1cc(F)c(c(F)c1)-n1c(C)cc(OCc2ccc(F)cc2F)c(Cl)c1=O |(32.8,-38.3,;31.47,-37.53,;30.13,-38.29,;28.8,-37.52,;28.81,-35.99,;30.14,-35.21,;31.47,-35.99,;27.48,-35.22,;27.48,-33.67,;26.14,-32.9,;26.14,-31.36,;24.82,-33.67,;24.81,-35.21,;23.48,-35.98,;26.14,-35.98,;23.49,-32.9,;23.49,-31.36,;24.82,-30.59,;22.16,-30.58,;20.83,-31.36,;19.49,-30.59,;18.16,-31.37,;16.83,-30.6,;15.51,-31.38,;14.17,-30.62,;14.16,-29.07,;12.82,-28.31,;15.49,-28.3,;16.83,-29.06,;18.16,-28.29,;20.83,-32.9,;19.5,-33.67,;22.16,-33.66,;22.16,-35.2,)| Show InChI InChI=1S/C24H22ClF4N3O2/c1-14-9-21(34-13-15-3-4-16(26)10-18(15)27)22(25)24(33)32(14)23-19(28)11-17(12-20(23)29)31-7-5-30(2)6-8-31/h3-4,9-12H,5-8,13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as phosphorylation of fluorescently-labelled MK2 using Hsp27 peptide as substrate after 60 mins by fluorescence assay				Bioorg Med Chem Lett 21: 4059-65 (2011) Article DOI: 10.1016/j.bmcl.2011.04.120 BindingDB Entry DOI: 10.7270/Q25Q4WFH
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