Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50347931'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50347931 (CHEMBL1802634) Show SMILES CNC(=O)c1ccc(c(C)c1)-n1c(C)cc(OCc2ccc(F)cc2F)c(Br)c1=O |(41.54,-12.31,;40.21,-11.54,;38.88,-12.31,;38.88,-13.85,;37.54,-11.55,;36.21,-12.32,;34.87,-11.55,;34.88,-10.01,;36.2,-9.24,;36.19,-7.7,;37.53,-10,;33.54,-9.24,;33.54,-7.69,;34.87,-6.92,;32.2,-6.93,;30.88,-7.7,;29.54,-6.93,;28.21,-7.7,;26.87,-6.93,;25.55,-7.7,;24.22,-6.94,;24.21,-5.39,;22.88,-4.62,;25.55,-4.62,;26.88,-5.39,;28.22,-4.62,;30.87,-9.24,;29.54,-10.01,;32.21,-10.02,;32.21,-11.56,)| Show InChI InChI=1S/C22H19BrF2N2O3/c1-12-8-14(21(28)26-3)5-7-18(12)27-13(2)9-19(20(23)22(27)29)30-11-15-4-6-16(24)10-17(15)25/h4-10H,11H2,1-3H3,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as phosphorylation FITC-labeled Hsp27 after 60 mins by fluorescence based cascade assay				Bioorg Med Chem Lett 21: 4066-71 (2011) Article DOI: 10.1016/j.bmcl.2011.04.121 BindingDB Entry DOI: 10.7270/Q2SB46R2
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