Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50357892'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50357892 (CHEMBL1916349) Show SMILES [O-][n+]1ccc2c(ccnc2c1-c1c(Cl)cccc1Cl)-c1ccc(F)cc1F |(1.17,-37.04,;2.5,-36.27,;2.5,-34.73,;3.83,-33.96,;5.17,-34.72,;6.5,-33.95,;7.84,-34.72,;7.84,-36.27,;6.49,-37.04,;5.16,-36.27,;3.83,-37.04,;3.84,-38.58,;2.5,-39.35,;1.17,-38.58,;2.51,-40.89,;3.84,-41.65,;5.18,-40.87,;5.17,-39.34,;6.5,-38.56,;6.5,-32.41,;5.17,-31.65,;5.16,-30.11,;6.5,-29.33,;6.5,-27.79,;7.84,-30.11,;7.84,-31.64,;9.17,-32.42,)| Show InChI InChI=1S/C20H10Cl2F2N2O/c21-15-2-1-3-16(22)18(15)20-19-14(7-9-26(20)27)12(6-8-25-19)13-5-4-11(23)10-17(13)24/h1-10H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of human p38alpha MAP kinase after 1 hr by FRET analysis				J Med Chem 54: 7899-910 (2011) Article DOI: 10.1021/jm200975u BindingDB Entry DOI: 10.7270/Q2MW2HKR
					More data for this Ligand-Target Pair