Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50418604'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50418604 (CHEMBL1784170) Show SMILES COCCNC(=O)c1ccc(cc1)-c1cc(cc(F)c1C)C(=O)NC1CC1 Show InChI InChI=1S/C21H23FN2O3/c1-13-18(11-16(12-19(13)22)21(26)24-17-7-8-17)14-3-5-15(6-4-14)20(25)23-9-10-27-2/h3-6,11-12,17H,7-10H2,1-2H3,(H,23,25)(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged p38alpha by fluorescence polarization method				J Med Chem 52: 6257-69 (2009) Article DOI: 10.1021/jm9004779 BindingDB Entry DOI: 10.7270/Q2J967NC
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50418604 (CHEMBL1784170) Show SMILES COCCNC(=O)c1ccc(cc1)-c1cc(cc(F)c1C)C(=O)NC1CC1 Show InChI InChI=1S/C21H23FN2O3/c1-13-18(11-16(12-19(13)22)21(26)24-17-7-8-17)14-3-5-15(6-4-14)20(25)23-9-10-27-2/h3-6,11-12,17H,7-10H2,1-2H3,(H,23,25)(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of p38alpha-dependent TNFalpha production in human whole blood preincubated for 1 hr before LPS challenge by ELISA				J Med Chem 52: 6257-69 (2009) Article DOI: 10.1021/jm9004779 BindingDB Entry DOI: 10.7270/Q2J967NC
					More data for this Ligand-Target Pair