Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50418608'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50418608 (CHEMBL1784174) Show SMILES CC(C)[C@@H](C)NC(=O)c1ccc(nc1)-c1cc(cc(F)c1C)C(=O)NC1CC1 |r| Show InChI InChI=1S/C22H26FN3O2/c1-12(2)14(4)25-21(27)15-5-8-20(24-11-15)18-9-16(10-19(23)13(18)3)22(28)26-17-6-7-17/h5,8-12,14,17H,6-7H2,1-4H3,(H,25,27)(H,26,28)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-tagged p38alpha by fluorescence polarization method				J Med Chem 52: 6257-69 (2009) Article DOI: 10.1021/jm9004779 BindingDB Entry DOI: 10.7270/Q2J967NC
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50418608 (CHEMBL1784174) Show SMILES CC(C)[C@@H](C)NC(=O)c1ccc(nc1)-c1cc(cc(F)c1C)C(=O)NC1CC1 |r| Show InChI InChI=1S/C22H26FN3O2/c1-12(2)14(4)25-21(27)15-5-8-20(24-11-15)18-9-16(10-19(23)13(18)3)22(28)26-17-6-7-17/h5,8-12,14,17H,6-7H2,1-4H3,(H,25,27)(H,26,28)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19.9	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of p38alpha-dependent TNFalpha production in human whole blood preincubated for 1 hr before LPS challenge by ELISA				J Med Chem 52: 6257-69 (2009) Article DOI: 10.1021/jm9004779 BindingDB Entry DOI: 10.7270/Q2J967NC
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50418608 (CHEMBL1784174) Show SMILES CC(C)[C@@H](C)NC(=O)c1ccc(nc1)-c1cc(cc(F)c1C)C(=O)NC1CC1 |r| Show InChI InChI=1S/C22H26FN3O2/c1-12(2)14(4)25-21(27)15-5-8-20(24-11-15)18-9-16(10-19(23)13(18)3)22(28)26-17-6-7-17/h5,8-12,14,17H,6-7H2,1-4H3,(H,25,27)(H,26,28)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63.1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of p38alpha-dependent TNFalpha production in human PBMC preincubated for 1 hr before LPS challenge by ELISA				J Med Chem 52: 6257-69 (2009) Article DOI: 10.1021/jm9004779 BindingDB Entry DOI: 10.7270/Q2J967NC
					More data for this Ligand-Target Pair