Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 11' and Ligand = 'BDBM354749'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354749 (Preparation of 4-(5-(3,4-dimethoxyphenyl)-1H-pyrro...) Show SMILES COc1ccc(cc1OC)-c1cnc2[nH]cc(-c3ccc(cc3)C(N)=O)c2c1 Show InChI InChI=1S/C22H19N3O3/c1-27-19-8-7-15(10-20(19)28-2)16-9-17-18(12-25-22(17)24-11-16)13-3-5-14(6-4-13)21(23)26/h3-12H,1-2H3,(H2,23,26)(H,24,25)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester; Board of Regents of the University of Nebraska US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US10485800 (2019) BindingDB Entry DOI: 10.7270/Q22B91DW
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354749 (Preparation of 4-(5-(3,4-dimethoxyphenyl)-1H-pyrro...) Show SMILES COc1ccc(cc1OC)-c1cnc2[nH]cc(-c3ccc(cc3)C(N)=O)c2c1 Show InChI InChI=1S/C22H19N3O3/c1-27-19-8-7-15(10-20(19)28-2)16-9-17-18(12-25-22(17)24-11-16)13-3-5-14(6-4-13)21(23)26/h3-12H,1-2H3,(H2,23,26)(H,24,25)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US9814704 (2017) BindingDB Entry DOI: 10.7270/Q27H1MRN
					More data for this Ligand-Target Pair