Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 12' and Ligand = 'BDBM301519'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human))	BDBM301519 (US10131675, Example 4) Show SMILES Cc1c[nH]c2ncc(cc12)-c1nc(N2CC(F)C2)c2nc3n(CCOC3(C)C)c2n1 Show InChI InChI=1S/C21H22FN7O/c1-11-7-23-17-14(11)6-12(8-24-17)16-26-18(28-9-13(22)10-28)15-19(27-16)29-4-5-30-21(2,3)20(29)25-15/h6-8,13H,4-5,9-10H2,1-3H3,(H,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	9.74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...				US Patent US10131675 (2018) BindingDB Entry DOI: 10.7270/Q21G0P92
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