Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 12' and Ligand = 'BDBM365242'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human))	BDBM365242 ((4-Chloro-pyridin-2-yl)- [2-(3,3-difluoro-pyrrolid...) Show SMILES FC1(F)CCN(C1)c1nc(Nc2cc(Cl)ccn2)cc(n1)C1CCNCC1 Show InChI InChI=1S/C18H21ClF2N6/c19-13-3-7-23-15(9-13)25-16-10-14(12-1-5-22-6-2-12)24-17(26-16)27-8-4-18(20,21)11-27/h3,7,9-10,12,22H,1-2,4-6,8,11H2,(H,23,24,25,26)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2J38VWN
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