Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 12' and Ligand = 'BDBM365248'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human))	BDBM365248 (US9868720, No. 160 | [2-(3,3-Difluoro-pyrrolidin- ...) Show SMILES CN1CCC(CC1)c1cc(Nc2cc(ccn2)C(F)(F)F)nc(n1)N1CCC(F)(F)C1 Show InChI InChI=1S/C20H23F5N6/c1-30-7-3-13(4-8-30)15-11-17(28-16-10-14(2-6-26-16)20(23,24)25)29-18(27-15)31-9-5-19(21,22)12-31/h2,6,10-11,13H,3-5,7-9,12H2,1H3,(H,26,27,28,29)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2J38VWN
					More data for this Ligand-Target Pair