Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 12' and Ligand = 'BDBM365253'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human))	BDBM365253 (3-{4-[2-(2-Methyl-pyrrolidin- 1-yl)-6-(4-trifluoro...) Show SMILES CC1CCCN1c1nc(Nc2cc(ccn2)C(F)(F)F)cc(n1)C1CCN(CC1)C(=O)CC#N Show InChI InChI=1S/C23H26F3N7O/c1-15-3-2-10-33(15)22-29-18(16-6-11-32(12-7-16)21(34)4-8-27)14-20(31-22)30-19-13-17(5-9-28-19)23(24,25)26/h5,9,13-16H,2-4,6-7,10-12H2,1H3,(H,28,29,30,31)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.03	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2J38VWN
					More data for this Ligand-Target Pair