Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 12' and Ligand = 'BDBM365260'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human))	BDBM365260 ((4-Cyclopropyl-pyridin- 2-yl)-[2-((R)-2-methyl- py...) Show SMILES C[C@@H]1CCCN1c1nc(Nc2cc(ccn2)C2CC2)cc(n1)C1CCNCC1 |r| Show InChI InChI=1S/C22H30N6/c1-15-3-2-12-28(15)22-25-19(17-6-9-23-10-7-17)14-21(27-22)26-20-13-18(8-11-24-20)16-4-5-16/h8,11,13-17,23H,2-7,9-10,12H2,1H3,(H,24,25,26,27)/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.950	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2J38VWN
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