Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 12' and Ligand = 'BDBM365261'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human))	BDBM365261 (2-Imidazol-1-yl-1-{3-[2- (2-methyl-pyrrolidin-1- y...) Show SMILES CC1CCCN1c1nc(Nc2cc(ccn2)C(F)(F)F)cc(n1)C1CCN(C1)C(=O)Cn1ccnc1 Show InChI InChI=1S/C24H27F3N8O/c1-16-3-2-8-35(16)23-30-19(17-5-9-34(13-17)22(36)14-33-10-7-28-15-33)12-21(32-23)31-20-11-18(4-6-29-20)24(25,26)27/h4,6-7,10-12,15-17H,2-3,5,8-9,13-14H2,1H3,(H,29,30,31,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2J38VWN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human))	BDBM365261 (2-Imidazol-1-yl-1-{3-[2- (2-methyl-pyrrolidin-1- y...) Show SMILES CC1CCCN1c1nc(Nc2cc(ccn2)C(F)(F)F)cc(n1)C1CCN(C1)C(=O)Cn1ccnc1 Show InChI InChI=1S/C24H27F3N8O/c1-16-3-2-8-35(16)23-30-19(17-5-9-34(13-17)22(36)14-33-10-7-28-15-33)12-21(32-23)31-20-11-18(4-6-29-20)24(25,26)27/h4,6-7,10-12,15-17H,2-3,5,8-9,13-14H2,1H3,(H,29,30,31,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2J38VWN
					More data for this Ligand-Target Pair