Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 12' and Ligand = 'BDBM365292'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human))	BDBM365292 (US9868720, No. 388 | {2-(2-Methyl-2H-pyrazol- 3-yl...) Show SMILES Cn1nccc1-c1nc(Nc2cc(ccn2)C(F)(F)F)cc(n1)C1CCN(CC2CCOCC2)C1 Show InChI InChI=1S/C24H28F3N7O/c1-33-20(3-8-29-33)23-30-19(17-4-9-34(15-17)14-16-5-10-35-11-6-16)13-22(32-23)31-21-12-18(2-7-28-21)24(25,26)27/h2-3,7-8,12-13,16-17H,4-6,9-11,14-15H2,1H3,(H,28,30,31,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2J38VWN
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