Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 12' and Ligand = 'BDBM365293'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human))	BDBM365293 (US9868720, No. 391 | [2-Cyclopentyl-6-(1- oxetan-3...) Show SMILES FC(F)(F)c1ccnc(Nc2cc(nc(n2)C2CCCC2)C2CCCN(C2)C2COC2)c1 Show InChI InChI=1S/C23H28F3N5O/c24-23(25,26)17-7-8-27-20(10-17)29-21-11-19(28-22(30-21)15-4-1-2-5-15)16-6-3-9-31(12-16)18-13-32-14-18/h7-8,10-11,15-16,18H,1-6,9,12-14H2,(H,27,28,29,30)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2J38VWN
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