Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 12' and Ligand = 'BDBM50128337'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human))	BDBM50128337 (CHEMBL3629018) Show SMILES N#Cc1ccnc(Nc2cc(C3CN(C3)C3COC3)n(n2)C2CCCC2)c1 Show InChI InChI=1S/C20H24N6O/c21-9-14-5-6-22-19(7-14)23-20-8-18(26(24-20)16-3-1-2-4-16)15-10-25(11-15)17-12-27-13-17/h5-8,15-17H,1-4,10-13H2,(H,22,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
WuXi AppTec Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of N-terminally GST- tagged human DLK catalytic domain (1 to 520 amino acids) using N-terminally HIS-tagged MKK4 K131M as substrate incuba...				J Med Chem 58: 8182-99 (2015) Article DOI: 10.1021/acs.jmedchem.5b01072 BindingDB Entry DOI: 10.7270/Q27D2WZ0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human))	BDBM50128337 (CHEMBL3629018) Show SMILES N#Cc1ccnc(Nc2cc(C3CN(C3)C3COC3)n(n2)C2CCCC2)c1 Show InChI InChI=1S/C20H24N6O/c21-9-14-5-6-22-19(7-14)23-20-8-18(26(24-20)16-3-1-2-4-16)15-10-25(11-15)17-12-27-13-17/h5-8,15-17H,1-4,10-13H2,(H,22,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	459	n/a	n/a	n/a	n/a	n/a	n/a
WuXi AppTec Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of Dox inducible human DLK transfected in HEK293 cells assessed as reduction in JNK phosphorylation incubated for 5.5 hrs measured by Hoec...				J Med Chem 58: 8182-99 (2015) Article DOI: 10.1021/acs.jmedchem.5b01072 BindingDB Entry DOI: 10.7270/Q27D2WZ0
					More data for this Ligand-Target Pair