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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 12' and Ligand = 'BDBM50128341'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase kinase kinase 12


(Homo sapiens (Human))		BDBM50128341
PNG
(CHEMBL3629174)
Show SMILES N#Cc1ccnc(Nc2cn(C3CCN(CC3)C3COC3)c(n2)C2CCCC2)c1
Show InChI InChI=1S/C22H28N6O/c23-12-16-5-8-24-20(11-16)25-21-13-28(22(26-21)17-3-1-2-4-17)18-6-9-27(10-7-18)19-14-29-15-19/h5,8,11,13,17-19H,1-4,6-7,9-10,14-15H2,(H,24,25)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.60E+3n/an/an/an/an/an/an/an/a



WuXi AppTec Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of N-terminally GST- tagged human DLK catalytic domain (1 to 520 amino acids) using N-terminally HIS-tagged MKK4 K131M as substrate incuba...

J Med Chem 58: 8182-99 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01072
BindingDB Entry DOI: 10.7270/Q27D2WZ0
More data for this
Ligand-Target Pair