Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 5' and Ligand = 'BDBM307616'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM307616 (N-cyclopropyl-2-(6- (4-cyclopropyl-4H- 1,2,4-triaz...) Show SMILES O=C(NC1CC1)c1ccc2C(=O)N(Cc2c1)c1cccc(n1)-c1nncn1C1CC1 Show InChI InChI=1S/C22H20N6O2/c29-21(24-15-5-6-15)13-4-9-17-14(10-13)11-27(22(17)30)19-3-1-2-18(25-19)20-26-23-12-28(20)16-7-8-16/h1-4,9-10,12,15-16H,5-8,11H2,(H,24,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SEAL ROCK THERAPEUTICS, INC. US Patent					Assay Description The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...				US Patent US10150755 (2018) BindingDB Entry DOI: 10.7270/Q2125VQ8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM307616 (N-cyclopropyl-2-(6- (4-cyclopropyl-4H- 1,2,4-triaz...) Show SMILES O=C(NC1CC1)c1ccc2C(=O)N(Cc2c1)c1cccc(n1)-c1nncn1C1CC1 Show InChI InChI=1S/C22H20N6O2/c29-21(24-15-5-6-15)13-4-9-17-14(10-13)11-27(22(17)30)19-3-1-2-18(25-19)20-26-23-12-28(20)16-7-8-16/h1-4,9-10,12,15-16H,5-8,11H2,(H,24,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
SEAL ROCK THERAPEUTICS, INC. US Patent					Assay Description The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...				US Patent US10150755 (2018) BindingDB Entry DOI: 10.7270/Q27P91GS
					More data for this Ligand-Target Pair