Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 5' and Ligand = 'BDBM307645'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM307645 (2-(6-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)pyridin-...) Show SMILES O=C1N(Cc2ccc(cc12)-n1ccnc1)c1cccc(n1)-c1nncn1C1CC1 Show InChI InChI=1S/C21H17N7O/c29-21-17-10-16(26-9-8-22-12-26)5-4-14(17)11-27(21)19-3-1-2-18(24-19)20-25-23-13-28(20)15-6-7-15/h1-5,8-10,12-13,15H,6-7,11H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SEAL ROCK THERAPEUTICS, INC. US Patent					Assay Description The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...				US Patent US10150755 (2018) BindingDB Entry DOI: 10.7270/Q2125VQ8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM307645 (2-(6-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)pyridin-...) Show SMILES O=C1N(Cc2ccc(cc12)-n1ccnc1)c1cccc(n1)-c1nncn1C1CC1 Show InChI InChI=1S/C21H17N7O/c29-21-17-10-16(26-9-8-22-12-26)5-4-14(17)11-27(21)19-3-1-2-18(24-19)20-25-23-13-28(20)15-6-7-15/h1-5,8-10,12-13,15H,6-7,11H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
SEAL ROCK THERAPEUTICS, INC. US Patent					Assay Description The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...				US Patent US10150755 (2018) BindingDB Entry DOI: 10.7270/Q27P91GS
					More data for this Ligand-Target Pair