Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 5' and Ligand = 'BDBM307687'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM307687 ((R)-2-(6-(5-(hydroxymethyl)-6,7-dihydro-5H-pyrrolo...) Show SMILES OC[C@H]1CCc2nnc(-c3cccc(n3)N3Cc4ccccc4C3=O)n12 |r| Show InChI InChI=1S/C19H17N5O2/c25-11-13-8-9-17-21-22-18(24(13)17)15-6-3-7-16(20-15)23-10-12-4-1-2-5-14(12)19(23)26/h1-7,13,25H,8-11H2/t13-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SEAL ROCK THERAPEUTICS, INC. US Patent					Assay Description The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...				US Patent US10150755 (2018) BindingDB Entry DOI: 10.7270/Q2125VQ8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM307687 ((R)-2-(6-(5-(hydroxymethyl)-6,7-dihydro-5H-pyrrolo...) Show SMILES OC[C@H]1CCc2nnc(-c3cccc(n3)N3Cc4ccccc4C3=O)n12 |r| Show InChI InChI=1S/C19H17N5O2/c25-11-13-8-9-17-21-22-18(24(13)17)15-6-3-7-16(20-15)23-10-12-4-1-2-5-14(12)19(23)26/h1-7,13,25H,8-11H2/t13-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
SEAL ROCK THERAPEUTICS, INC. US Patent					Assay Description The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...				US Patent US10150755 (2018) BindingDB Entry DOI: 10.7270/Q27P91GS
					More data for this Ligand-Target Pair