Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 8' and Ligand = 'BDBM50173830'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 8 (Homo sapiens (Human))	BDBM50173830 ((S)-4-(3-chloro-4-fluorophenylamino)-6-(1-phenylet...) Show SMILES C[C@H](Nc1cc2c(Nc3ccc(F)c(Cl)c3)c(cnc2cn1)C#N)c1ccccc1 |r| Show InChI InChI=1S/C23H17ClFN5/c1-14(15-5-3-2-4-6-15)29-22-10-18-21(13-28-22)27-12-16(11-26)23(18)30-17-7-8-20(25)19(24)9-17/h2-10,12-14H,1H3,(H,27,30)(H,28,29)/t14-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against human Tpl2 kinase via quantification of MEK phosphorylation				Bioorg Med Chem Lett 15: 5288-92 (2005) Article DOI: 10.1016/j.bmcl.2005.08.029 BindingDB Entry DOI: 10.7270/Q2JS9Q0M
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 8 (Homo sapiens (Human))	BDBM50173830 ((S)-4-(3-chloro-4-fluorophenylamino)-6-(1-phenylet...) Show SMILES C[C@H](Nc1cc2c(Nc3ccc(F)c(Cl)c3)c(cnc2cn1)C#N)c1ccccc1 |r| Show InChI InChI=1S/C23H17ClFN5/c1-14(15-5-3-2-4-6-15)29-22-10-18-21(13-28-22)27-12-16(11-26)23(18)30-17-7-8-20(25)19(24)9-17/h2-10,12-14H,1H3,(H,27,30)(H,28,29)/t14-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human Tpl2 by ELISA				J Biol Chem 282: 33295-304 (2007) Article DOI: 10.1074/jbc.M703694200 BindingDB Entry DOI: 10.7270/Q2KS6RBP
					More data for this Ligand-Target Pair