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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 8' and Ligand = 'BDBM50195001'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase kinase kinase 8


(Homo sapiens (Human))
BDBM50195001
PNG
(4-(3-chloro-4-fluorophenylamino)-6-(furan-2-ylmeth...)
Show SMILES Fc1ccc(Nc2c(cnc3ccc(NCc4ccco4)cc23)C#N)cc1Cl
Show InChI InChI=1S/C21H14ClFN4O/c22-18-9-15(3-5-19(18)23)27-21-13(10-24)11-26-20-6-4-14(8-17(20)21)25-12-16-2-1-7-28-16/h1-9,11,25H,12H2,(H,26,27)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 240n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of Tpl2 kinase by ELISA


Bioorg Med Chem Lett 16: 6067-72 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.102
BindingDB Entry DOI: 10.7270/Q2W958TR
More data for this
Ligand-Target Pair