Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 8' and Ligand = 'BDBM50195002'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 8 (Homo sapiens (Human))	BDBM50195002 (4-(3-chloro-4-fluorophenoxy)-6-(2-morpholinoethyla...) Show SMILES Fc1ccc(Oc2c(cnc3ccc(NCCN4CCOCC4)cc23)C#N)cc1Cl Show InChI InChI=1S/C22H20ClFN4O2/c23-19-12-17(2-3-20(19)24)30-22-15(13-25)14-27-21-4-1-16(11-18(21)22)26-5-6-28-7-9-29-10-8-28/h1-4,11-12,14,26H,5-10H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of Tpl2 kinase by ELISA				Bioorg Med Chem Lett 16: 6067-72 (2006) Article DOI: 10.1016/j.bmcl.2006.08.102 BindingDB Entry DOI: 10.7270/Q2W958TR
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