new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 8' and Ligand = 'BDBM50195005'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase kinase kinase 8


(Homo sapiens (Human))
BDBM50195005
PNG
(6-(3-cyanobenzylamino)-4-(3-chloro-4-fluorophenyla...)
Show SMILES Fc1ccc(Nc2c(cnc3ccc(NCc4cccc(c4)C#N)cc23)C#N)cc1Cl
Show InChI InChI=1S/C24H15ClFN5/c25-21-10-19(4-6-22(21)26)31-24-17(12-28)14-30-23-7-5-18(9-20(23)24)29-13-16-3-1-2-15(8-16)11-27/h1-10,14,29H,13H2,(H,30,31)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 100n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of Tpl2 kinase by ELISA


Bioorg Med Chem Lett 16: 6067-72 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.102
BindingDB Entry DOI: 10.7270/Q2W958TR
More data for this
Ligand-Target Pair