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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 8' and Ligand = 'BDBM50195012'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase kinase kinase 8


(Homo sapiens (Human))
BDBM50195012
PNG
(6-((1H-imidazol-4-yl)methylamino)-4-(3-chloro-4-fl...)
Show SMILES Cc1nc2ccc(NCc3cnc[nH]3)cc2c(Nc2ccc(F)c(Cl)c2)c1C#N
Show InChI InChI=1S/C21H16ClFN6/c1-12-17(8-24)21(29-14-2-4-19(23)18(22)7-14)16-6-13(3-5-20(16)28-12)26-10-15-9-25-11-27-15/h2-7,9,11,26H,10H2,1H3,(H,25,27)(H,28,29)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.90E+4n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of Tpl2 kinase by ELISA


Bioorg Med Chem Lett 16: 6067-72 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.102
BindingDB Entry DOI: 10.7270/Q2W958TR
More data for this
Ligand-Target Pair