Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 8' and Ligand = 'BDBM50265349'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 8 (Homo sapiens (Human))	BDBM50265349 (4-(2'-methoxybiphenyl-4-yloxy)-2-(2H-tetrazol-5-yl...) Show SMILES COc1ccccc1-c1ccc(Oc2cncc3sc(cc23)-c2nnn[nH]2)cc1 Show InChI InChI=1S/C21H15N5O2S/c1-27-17-5-3-2-4-15(17)13-6-8-14(9-7-13)28-18-11-22-12-20-16(18)10-19(29-20)21-23-25-26-24-21/h2-12H,1H3,(H,23,24,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Bioresearch Center Curated by ChEMBL					Assay Description Inhibition of human recombinant COT by HTRF-based assay				Bioorg Med Chem Lett 18: 4952-5 (2008) Article DOI: 10.1016/j.bmcl.2008.08.037 BindingDB Entry DOI: 10.7270/Q23J3CTH
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