Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase kinase 4' and Ligand = 'BDBM50011554'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011554 (CHEMBL3262573 | US9592235, Example 166 | US9855269...) Show SMILES COc1ccc(cc1)-c1ccc2ncnc(N)c2c1 Show InChI InChI=1S/C15H13N3O/c1-19-12-5-2-10(3-6-12)11-4-7-14-13(8-11)15(16)18-9-17-14/h2-9H,1H3,(H2,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	689	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assay				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011554 (CHEMBL3262573 | US9592235, Example 166 | US9855269...) Show SMILES COc1ccc(cc1)-c1ccc2ncnc(N)c2c1 Show InChI InChI=1S/C15H13N3O/c1-19-12-5-2-10(3-6-12)11-4-7-14-13(8-11)15(16)18-9-17-14/h2-9H,1H3,(H2,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research					Assay Description The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...				J Med Chem 46: 3709-27 (2003) BindingDB Entry DOI: 10.7270/Q2VH5R4B
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011554 (CHEMBL3262573 | US9592235, Example 166 | US9855269...) Show SMILES COc1ccc(cc1)-c1ccc2ncnc(N)c2c1 Show InChI InChI=1S/C15H13N3O/c1-19-12-5-2-10(3-6-12)11-4-7-14-13(8-11)15(16)18-9-17-14/h2-9H,1H3,(H2,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...				US Patent US9592235 (2017) BindingDB Entry DOI: 10.7270/Q2VX0JKX
					More data for this Ligand-Target Pair