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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase kinase 4' and Ligand = 'BDBM50058661'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase kinase kinase kinase 4


(Homo sapiens (Human))
BDBM50058661
PNG
(CHEMBL3326763)
Show SMILES CNS(=O)(=O)c1ccc(cc1)-c1cc2c(Nc3ccncc3)ncnn2c1
Show InChI InChI=1S/C18H16N6O2S/c1-19-27(25,26)16-4-2-13(3-5-16)14-10-17-18(21-12-22-24(17)11-14)23-15-6-8-20-9-7-15/h2-12,19H,1H3,(H,20,21,22,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of human MAP4K4 using LGRDKYKTLRQIRQ-COOH peptide substrate by LC3K assay


Bioorg Med Chem Lett 24: 4546-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.07.071
BindingDB Entry DOI: 10.7270/Q2NG4S9D
More data for this
Ligand-Target Pair