Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase kinase 4' and Ligand = 'BDBM50138135'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50138135 (CHEMBL3754762) Show SMILES Nc1ncc(cc1-c1ccc(Cl)cc1)-c1ccc(=O)[nH]c1 Show InChI InChI=1S/C16H12ClN3O/c17-13-4-1-10(2-5-13)14-7-12(9-20-16(14)18)11-3-6-15(21)19-8-11/h1-9H,(H2,18,20)(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assay				ACS Med Chem Lett 6: 1128-33 (2015) Article DOI: 10.1021/acsmedchemlett.5b00215 BindingDB Entry DOI: 10.7270/Q2028TC6
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50138135 (CHEMBL3754762) Show SMILES Nc1ncc(cc1-c1ccc(Cl)cc1)-c1ccc(=O)[nH]c1 Show InChI InChI=1S/C16H12ClN3O/c17-13-4-1-10(2-5-13)14-7-12(9-20-16(14)18)11-3-6-15(21)19-8-11/h1-9H,(H2,18,20)(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human MAP4K4 transfected in 293 MSR cells assessed as inhibition of phosphorylation of traf2 at ser/thr residue by ELISA				ACS Med Chem Lett 6: 1128-33 (2015) Article DOI: 10.1021/acsmedchemlett.5b00215 BindingDB Entry DOI: 10.7270/Q2028TC6
					More data for this Ligand-Target Pair