new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Monoamine oxidase' and Ligand = 'BDBM50359392'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoamine oxidase


(Rattus norvegicus (rat))
BDBM50359392
PNG
(CHEMBL1929424 | US8999994, 3)
Show SMILES CN(CC#C)Cc1cc2cc(OCCCN3CCN(Cc4ccccc4)CC3)ccc2n1C
Show InChI InChI=1S/C28H36N4O/c1-4-13-29(2)23-26-20-25-21-27(11-12-28(25)30(26)3)33-19-8-14-31-15-17-32(18-16-31)22-24-9-6-5-7-10-24/h1,5-7,9-12,20-21H,8,13-19,22-23H2,2-3H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 31n/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of rat liver mitochondrial MAO-A using [14C]-5-hydroxytryptamine after 30 mins by scintillation counting


J Med Chem 54: 8251-70 (2011)


Article DOI: 10.1021/jm200853t
BindingDB Entry DOI: 10.7270/Q20P10G5
More data for this
Ligand-Target Pair
Monoamine oxidase


(Rattus norvegicus (rat))
BDBM50359392
PNG
(CHEMBL1929424 | US8999994, 3)
Show SMILES CN(CC#C)Cc1cc2cc(OCCCN3CCN(Cc4ccccc4)CC3)ccc2n1C
Show InChI InChI=1S/C28H36N4O/c1-4-13-29(2)23-26-20-25-21-27(11-12-28(25)30(26)3)33-19-8-14-31-15-17-32(18-16-31)22-24-9-6-5-7-10-24/h1,5-7,9-12,20-21H,8,13-19,22-23H2,2-3H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
US Patent
n/an/a 3.05E+4n/an/an/an/a7.437



Consejo Superior de Investigaciones Cientificas; Universitat Autonoma de Barcelona; Universidad de Barcelona

US Patent


Assay Description
The inhibitory activity of monoamine oxidases A and B was assessed by the Fowler and Tipton radiometric method (Biochem Pharmacol 1981, 30, 3329) usi...


US Patent US8999994 (2015)


BindingDB Entry DOI: 10.7270/Q2NZ86CM
More data for this
Ligand-Target Pair