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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Monocarboxylate Transporter 1' and Ligand = 'BDBM22014'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monocarboxylate Transporter 1


(Homo sapiens (Human))
BDBM22014
PNG
(5-{[(3R)-3-hydroxypyrrolidine-1-]sulfonyl}-3-methy...)
Show SMILES CC(C)Cn1c2sc(Cc3ccccc3C(F)(F)F)c(c2c(=O)n(C)c1=O)S(=O)(=O)N1CC[C@@H](O)C1 |r|
Show InChI InChI=1S/C23H26F3N3O5S2/c1-13(2)11-29-21-18(20(31)27(3)22(29)32)19(36(33,34)28-9-8-15(30)12-28)17(35-21)10-14-6-4-5-7-16(14)23(24,25)26/h4-7,13,15,30H,8-12H2,1-3H3/t15-/m1/s1
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UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
1.10 -50.6n/an/an/an/an/a7.822



AstraZeneca



Assay Description
Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...


Bioorg Med Chem Lett 16: 2260-5 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.024
BindingDB Entry DOI: 10.7270/Q2C24TQK
More data for this
Ligand-Target Pair