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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Monocarboxylate Transporter 1' and Ligand = 'BDBM22027'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monocarboxylate Transporter 1


(Homo sapiens (Human))
BDBM22027
PNG
(5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-meth...)
Show SMILES CNc1nc2ccccc2n1Cc1sc2n(CC(C)C)c(=O)n(C)c(=O)c2c1C(=O)N1CC[C@@H](O)C1 |r|
Show InChI InChI=1S/C25H30N6O4S/c1-14(2)11-31-23-20(21(33)28(4)25(31)35)19(22(34)29-10-9-15(32)12-29)18(36-23)13-30-17-8-6-5-7-16(17)27-24(30)26-3/h5-8,14-15,32H,9-13H2,1-4H3,(H,26,27)/t15-/m1/s1
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UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
6.60 -46.2n/an/an/an/an/a7.422



AstraZeneca



Assay Description
A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...


Bioorg Med Chem Lett 16: 2260-5 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.024
BindingDB Entry DOI: 10.7270/Q2C24TQK
More data for this
Ligand-Target Pair