Compile Data Set for Download or QSAR

Found 11 hits Enz. Inhib. hit(s) with Target = 'Monocarboxylate transporter 4' and Ligand = 'BDBM345268'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monocarboxylate transporter 4 (Homo sapiens (Human))	BDBM345268 (2-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxypheny...) Show SMILES COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1Cl Show InChI InChI=1S/C22H23ClN2O4/c1-22(2,21(26)27)29-14-17-12-20(15-8-6-9-18(11-15)28-3)25(24-17)13-16-7-4-5-10-19(16)23/h4-12H,13-14H2,1-3H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Vettore, LLC US Patent					Assay Description MCT4 may be stably expressed in MDA-MB-453 breast cancer cells that do not express native MCT1 or MCT4. MCT4 activity may be assessed by monitoring t...				US Patent US10214492 (2019) BindingDB Entry DOI: 10.7270/Q2Q81GC0
					More data for this Ligand-Target Pair
Monocarboxylate transporter 4 (Homo sapiens (Human))	BDBM345268 (2-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxypheny...) Show SMILES COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1Cl Show InChI InChI=1S/C22H23ClN2O4/c1-22(2,21(26)27)29-14-17-12-20(15-8-6-9-18(11-15)28-3)25(24-17)13-16-7-4-5-10-19(16)23/h4-12H,13-14H2,1-3H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2CR5ZGC
					More data for this Ligand-Target Pair
Monocarboxylate transporter 4 (Homo sapiens (Human))	BDBM345268 (2-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxypheny...) Show SMILES COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1Cl Show InChI InChI=1S/C22H23ClN2O4/c1-22(2,21(26)27)29-14-17-12-20(15-8-6-9-18(11-15)28-3)25(24-17)13-16-7-4-5-10-19(16)23/h4-12H,13-14H2,1-3H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Vettore, LLC US Patent					Assay Description MCT4 may be stably expressed in MDA-MB-453 breast cancer cells that do not express native MCT1 or MCT4. MCT4 activity may be assessed by monitoring t...				US Patent US10202350 (2019) BindingDB Entry DOI: 10.7270/Q20K2BPB
					More data for this Ligand-Target Pair
Monocarboxylate transporter 4 (Homo sapiens (Human))	BDBM345268 (2-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxypheny...) Show SMILES COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1Cl Show InChI InChI=1S/C22H23ClN2O4/c1-22(2,21(26)27)29-14-17-12-20(15-8-6-9-18(11-15)28-3)25(24-17)13-16-7-4-5-10-19(16)23/h4-12H,13-14H2,1-3H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Vettore, LLC US Patent					Assay Description MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...				US Patent US10202350 (2019) BindingDB Entry DOI: 10.7270/Q20K2BPB
					More data for this Ligand-Target Pair
Monocarboxylate transporter 4 (Homo sapiens (Human))	BDBM345268 (2-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxypheny...) Show SMILES COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1Cl Show InChI InChI=1S/C22H23ClN2O4/c1-22(2,21(26)27)29-14-17-12-20(15-8-6-9-18(11-15)28-3)25(24-17)13-16-7-4-5-10-19(16)23/h4-12H,13-14H2,1-3H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Vettore, LLC US Patent					Assay Description MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...				US Patent US10214492 (2019) BindingDB Entry DOI: 10.7270/Q2Q81GC0
					More data for this Ligand-Target Pair
Monocarboxylate transporter 4 (Homo sapiens (Human))	BDBM345268 (2-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxypheny...) Show SMILES COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1Cl Show InChI InChI=1S/C22H23ClN2O4/c1-22(2,21(26)27)29-14-17-12-20(15-8-6-9-18(11-15)28-3)25(24-17)13-16-7-4-5-10-19(16)23/h4-12H,13-14H2,1-3H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2862KNG
					More data for this Ligand-Target Pair
Monocarboxylate transporter 4 (Homo sapiens (Human))	BDBM345268 (2-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxypheny...) Show SMILES COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1Cl Show InChI InChI=1S/C22H23ClN2O4/c1-22(2,21(26)27)29-14-17-12-20(15-8-6-9-18(11-15)28-3)25(24-17)13-16-7-4-5-10-19(16)23/h4-12H,13-14H2,1-3H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2CR5ZGC
					More data for this Ligand-Target Pair
Monocarboxylate transporter 4 (Homo sapiens (Human))	BDBM345268 (2-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxypheny...) Show SMILES COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1Cl Show InChI InChI=1S/C22H23ClN2O4/c1-22(2,21(26)27)29-14-17-12-20(15-8-6-9-18(11-15)28-3)25(24-17)13-16-7-4-5-10-19(16)23/h4-12H,13-14H2,1-3H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2CR5ZGC
					More data for this Ligand-Target Pair
Monocarboxylate transporter 4 (Homo sapiens (Human))	BDBM345268 (2-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxypheny...) Show SMILES COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1Cl Show InChI InChI=1S/C22H23ClN2O4/c1-22(2,21(26)27)29-14-17-12-20(15-8-6-9-18(11-15)28-3)25(24-17)13-16-7-4-5-10-19(16)23/h4-12H,13-14H2,1-3H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known...				Citation and Details BindingDB Entry DOI: 10.7270/Q2862KNG
					More data for this Ligand-Target Pair
Monocarboxylate transporter 4 (Homo sapiens (Human))	BDBM345268 (2-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxypheny...) Show SMILES COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1Cl Show InChI InChI=1S/C22H23ClN2O4/c1-22(2,21(26)27)29-14-17-12-20(15-8-6-9-18(11-15)28-3)25(24-17)13-16-7-4-5-10-19(16)23/h4-12H,13-14H2,1-3H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Vettore, LLC US Patent					Assay Description NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known...				US Patent US10202350 (2019) BindingDB Entry DOI: 10.7270/Q20K2BPB
					More data for this Ligand-Target Pair
Monocarboxylate transporter 4 (Homo sapiens (Human))	BDBM345268 (2-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxypheny...) Show SMILES COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1Cl Show InChI InChI=1S/C22H23ClN2O4/c1-22(2,21(26)27)29-14-17-12-20(15-8-6-9-18(11-15)28-3)25(24-17)13-16-7-4-5-10-19(16)23/h4-12H,13-14H2,1-3H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Vettore, LLC US Patent					Assay Description NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known...				US Patent US10214492 (2019) BindingDB Entry DOI: 10.7270/Q2Q81GC0
					More data for this Ligand-Target Pair