Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442716 (CHEMBL2442510) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair |